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Image Search Results
Journal: Respiratory Research
Article Title: CXCL11 levels regulate lung Treg responses to deter the onset of HIV-related COPD
doi: 10.1186/s12931-026-03495-8
Figure Lengend Snippet: The effect of EcoHIV infection and cigarette smoke exposure on lung Cxcl11 expression. A Cxcl11 RT-PCR analysis was conducted on the lungs of EcoHIV infected A/J mice. Data is represented on the y-axis as relative expression compared to PBS treated air-exposed mice. Data is presented as mean ± SEM. ( N ≥ 9 per group). B Cxcl11 RT-PCR was performed on air and smoke exposed control and EcoHIV infected alveolar macrophages from A/J mice. Data is represented on the y-axis as relative expression compared to PBS treated air-exposed mice. Data is presented as mean ± SEM. ( N ≥ 3 per group). C A/J mice were inoculated once with PBS or EcoHIV and exposed to 2 months of room air (RA) or cigarette smoke. Cxcl11 levels in BALF of mice was quantified by ELISA. Data is expressed as mean ± SEM ( N ≥ 3/group)
Article Snippet: D Cxcl11 expression was measured by RT-PCR in
Techniques: Infection, Expressing, Reverse Transcription Polymerase Chain Reaction, Control, Enzyme-linked Immunosorbent Assay
Journal: Respiratory Research
Article Title: CXCL11 levels regulate lung Treg responses to deter the onset of HIV-related COPD
doi: 10.1186/s12931-026-03495-8
Figure Lengend Snippet: HuR and c-Src regulate CXCL11 expression in the lung. A CXCL11 mRNA expression was determined via RT-PCR in normal human airway epithelial cells that were treated with 100-ng/ml of actinomycin for a three-hour time period. p < 0.05 comparing the 0 and 1-hour timepoints with the 2 and 3-hour timepoints. B RT-PCR for CXCL11 was conducted as above on human airway epithelial cells treated with control, c-Src or HuR siRNA for 24 h. C Cxcl11 protein levels were measured by ELISA from the BALF of A/J mice treated orally with vehicle or 10 mg/kg AZD0530 while they were exposed to room air or cigarette smoke for one week. Data is presented as mean ± SEM. ( N ≥ 4 per group). D Cxcl11 expression was measured by RT-PCR in mouse alveolar macrophages (ATCC CRL2019) treated with vehicle or 1-mM AZD0530 with or without 5% CSE for 24 h ( N ≥ 6 per group). Data is expressed as relative quantification (RQ) compared to PBS/vehicle treated cells
Article Snippet: D Cxcl11 expression was measured by RT-PCR in
Techniques: Expressing, Reverse Transcription Polymerase Chain Reaction, Control, Enzyme-linked Immunosorbent Assay, Quantitative Proteomics